Day 1 :
Tanta faculty of medicine, Egypt
Ibrahim El Bayoumy has pursued his Bachelor’s degree of Medicine and Surgery, Tanta Faculty of Medicine, Tanta University, Egypt. He has completed his Master’s degree in Public Health, Preventive and Social Medicine, in Tanta University, Faculty of Medicine-Egypt. He is a full Professor of Public Health and Community Medicine in Tanta University, Faculty of Medicine, Egypt. Currently, he is working in Ministry of Health in Kuwait as Consultant of Public Health and Preventive Medicine.
The past 50 years have seen the development of many new treatment items in management of type-2 diabetes. Despite this success, it can be seen that the frequency of the disease complications and the socio-economic burden on communities with high prevalence of diabetes. Thus, the next 50 years will be critical if it is able to prevent and control the major non-communicable diseases like type-2 diabetes and cancer. It is hoped to get a great knowledge that will be acquired in the future from clinical studies results that will inform the treatment guidelines with regard to which agents to use in whom and whether more aggressive approaches can slow the development of hyperglycemia in those persons at high risk. Over that, it is expected to get new drugs and techniques for therapeutic intervention. These achievements will lead to more self-treatment approaches. Most importantly, the political and economic efforts on enhancing and implementing public health approaches can be focussed and aimed at prevention of diabetes and its co-morbidities.
- Prevention of Diabetes | Diabetes: Types & Pathophysiology | Diabetic Nephropathy| Glaucoma | Diabetes & Cancer | Probiotics and Antimicrobial Proteins | Probiotics in Diabetes | Functional Foods
Location: Ball Room 3
Jagiellonian University Medical College, Poland
Katarzyna W Jasinska is a Junior Researcher from Faculty of Medicine, Jagiellonian University Medical College in Cracow, Poland. She is an author of several published papers and numerous congress presentations. Her main research interests are probiotics and bariatric.
Introduction & Aim: Probiotics are living micro-organisms which may confer a health benefit on the host, allowing consider them as functional food. Numerous evidences suggest that probiotics have advantageous impact on diseases such as constipation, several types of diarrhea, irritable bowel syndrome, melioration of lactose intolerance, inhibition of Helicobacter pylori and reduction in serum cholesterol level. However, current evidence on the effect of probiotics on neurocognitive functions is limited. This systematic review aims to assess the efficacy of probiotics in dementia.
Methods: This is a systematic review conducted following Cochrane Handbook for Systematic Reviews of Interventions. Protocol of the study has been registered in PROSPERO at CRD42019123490. We have searched four electronic databases, three clinical trial registers and carried out a hand searching to find relevant studies. All titles and abstracts of studies were reviewed independently by two reviewers and eligible full texts were assessed similarly. To assess risk of bias in included studies we use Cochrane Risk of Bias Tool for RCTs.
Results: Searching identified 3088 records (3071 from databases and 17 additional from clinical trials registers). After removing duplicates, we screened 2548 references. We included 12 papers into full texts screening, 7 of them was included into qualitative synthesis. Main interventions used were Lactobacilli and Bifidobacteria. Predominantly evaluated dementia was related to Alzheimer’s disease and predementia state was related to minimal hepatic encephalopathy. All of the included studies have shown improvement in cognitive function in predementia, nevertheless results for severe dementia seems to be uncertain. One of the papers presents increase in quality of life after probiotic administration.
Conclusion: This review suggests the potential advantages of using probiotics in neurocognitive disorder. However, this field seems to be unexplored and more high quality RCTs is needed.
Diponegoro University, Indonesia
Laksmi Hartajanie has completed her PhD from Diponegoro University, Faculty of Medicine. She is a Senior Lecturer of Soegijapranata Catholic University, Faculty of Food Technology.
Momordica charantia (Bitter melon) contains substance with antidiabetic properties such as charantin that has anti-oxidative properties. Oxidative stress plays a major role in the pathogenesis and progression of metabolic syndrome such as diabetes. In the present study, a total of 30 male Sprague-Dawley rats were used. Diabetes type-2 was induced by a single dose (60 mg/kg) of Streptozotocin (STZ), intravenous injection. Following three days of STZ induction, the animals were randomly divided into five groups (n=6); diabetic group treated with Acarbose 40 mg/100 g feed (DM-Ac), diabetic group treated with MC (DM-MC), diabetic group treated with Probiotic 1 MC (DM-PMC1), diabetic group treated with probiotic 2 MC (DM-PMC2) and diabetic untreated group (DM-Ctrl). Oral administration of the MC fruit extract (10 ml/kg body weight) was continued for 28 days. All groups treated with MC (non-fermented and fermented) showed a significant decreased (P<0.05) in fasting blood glucose and post prandial blood glucose compared to the DM-Ctrl group. SOD level was significantly increased in MC groups. These results suggest that fermented bitter melon juice is a promising complimentary agent for diabetes type-2 treatment.
Dede Mahdiyah is a PhD candidate from Diponegoro University, Indonesia. She is currently working as a Lecturer and as Head of Research and Community Services of Sari Mulia University, Banjarmasin, South of Kalimantan.
The widespread use of antibiotics to treat infectious diseases causes a global increase of resistant bacteria, whereas a discovery of new antibiotics was very rare due to high expenses. Peat land has an extreme and unique environment therefore an adapted bacterial flora may has special metabolic properties which contain has antimicrobial like substances. The purpose of this study was to identify the characteristics of antibiotic like substances produced by peat soil bacteria. The TSA media incubate at 30oC for two days was used to isolate the bacteria. The isolated colonies were identified and followed by Gram staining and catalase test. Antimicrobial activity test towards Salmonella Typhi was done using diffusion wells method, incubate at 37oC for 24 hours and chloramphenicol disk was used as control. Molecular weight was determined by SDS PAGE electrophoresis. The characteristics of bacteria were Gram negative cocci, positive catalase with molecular weight of 43 KDa. Diameter of inhibition zone of peat soil bacteria is 30 mm, whereas chloramphenicol is 27.5 mm. Antibiotic-like substances produced by peat soil bacteria need to be further characterized and may be able to be developed as antibacterial drug.
Shengli Oilfield Central Hospital, China
Western University of Health Sciences, USA
Trent Brookshier is currently pursuing his Medical degree at College of Podiatric Medicine-Western University of Health Sciences (WUCPM). He has pursued his Bachelor in Science degree at UC Irvine.
Diabetes mellitus type-2 affects millions of Americans and is one of the leading causes of death. A few simple steps could make an enormous difference in the management of diabetes. Early detection, effective patient education and patient compliance are some of the ways in which the progression of the disease can be combated. The hypothesis was that using the term prediabetes is not the most effective label when counseling patients on hyperglycemia or insulin insufficiency. A survey testing the perception of prediabetes versus newly coined stage-1 diabetes was conducted to see if patients viewed them differently and how it would influence their decisions. It is found that patients viewed stage-1 diabetes 17% more severely on a ten-point scale and were 20% more likely to see the need for medication when this new name was used. None of those surveyed that currently were diagnosed with prediabetes were on medication but 66% said they would be willing to take medication if they were diagnosed with stage-1 diabetes. Based on the results of the study it is proposed using a new naming system for diabetes mellitus to help improve patient compliance and outcomes.
RSUD Dr. Saiful Anwar, Indonesia